{"id":2385,"date":"2026-06-01T04:02:33","date_gmt":"2026-06-01T04:02:33","guid":{"rendered":"https:\/\/yohopharm.com\/?p=2385"},"modified":"2026-06-01T06:22:04","modified_gmt":"2026-06-01T06:22:04","slug":"breakthrough-enzymes-revolutionize-icariin-to-boost-cancer-therapy","status":"publish","type":"post","link":"https:\/\/yohopharm.com\/es\/breakthrough-enzymes-revolutionize-icariin-to-boost-cancer-therapy\/","title":{"rendered":"Breakthrough: Enzymes Revolutionize Icariin to Boost Cancer Therapy"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"2385\" class=\"elementor elementor-2385\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-70c5c1c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"70c5c1c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-35e84ec\" data-id=\"35e84ec\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-41b77b3 elementor-widget elementor-widget-text-editor\" data-id=\"41b77b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"otQkpb\" style=\"font-family: Arial, sans-serif; font-size: 20px; font-weight: bold; margin: 24px 0px 12px; border-bottom: 0px #0a0a0a;\" role=\"heading\" aria-level=\"3\" data-animation-nesting=\"\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-processed=\"true\" data-sae=\"\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 20px; font-weight: 700; margin: 24px 0px 12px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"Yjhzub\" style=\"font-size: 16px; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">I<a href=\"https:\/\/yohopharm.com\/es\/producto\/epimedium-extract-20-icariin\/\">cariin<\/a><\/span><span style=\"font-size: 16px; font-weight: 400;\">, a compound derived from the precious Chinese medicinal herb Epimedium, shows significant therapeutic potential against liver cancer. However, extracting <\/span><span class=\"Yjhzub\" style=\"font-size: 16px; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">icariin<\/span><span style=\"font-size: 16px; font-weight: 400;\"> is notoriously difficult. Currently, most market manufacturers rely on chemical extraction or direct synthesis, which yield poor results and cause heavy pollution. While traditional enzymatic methods exist, they use standard commercial enzymes that only convert a single component, resulting in very low conversion rates.<\/span><\/div><div class=\"n6owBd awi2gc\" style=\"font-family: Arial, sans-serif; font-size: 16px; margin: 12px 0px 16px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAICBAA\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 12px 0px 16px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">To break this bottleneck, our company partnered with the &#8220;Enzyme Future&#8221; team from the College of Chemical Engineering to develop a game-changing solution. Targeting the specific traits of Epimedium total flavonoids, we utilized modern biotechnologies\u2014such as genetic modification and cloning expression\u2014to create a unique, highly efficient biological enzyme.<!--TgQPHd|[]--><\/div><div class=\"n6owBd awi2gc\" style=\"font-family: Arial, sans-serif; font-size: 16px; margin: 12px 0px 16px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAICRAA\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 12px 0px 16px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">This innovation delivers three core breakthroughs:<!--TgQPHd|[]--><\/div><ul class=\"KsbFXc U6u95\" style=\"font-family: Arial, sans-serif; font-size: 16px; margin: 12px 0px 16px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 12px 0px 16px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><li style=\"list-style-type: none;\"><ul class=\"KsbFXc U6u95\" style=\"font-family: Arial, sans-serif; font-size: 16px; margin: 12px 0px 16px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 12px 0px 16px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><li class=\"Z1qcYe\" style=\"font-size: 16px; margin: 0px 0px 12px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAIChAA\" data-complete=\"true\" data-sae=\"\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px 0px 12px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"T286Pc\" style=\"margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">5-in-1 Directional Conversion<!--TgQPHd|[]--><\/span>: This specialized enzyme directionally converts all 5 flagship flavonoids within Epimedium into <span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">icariin<!--TgQPHd|[]--><\/span>.<!--TgQPHd|[]--><\/span><!--TgQPHd|[]--><\/li><li class=\"Z1qcYe\" style=\"font-size: 16px; margin: 0px 0px 12px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAIChAD\" data-complete=\"true\" data-sae=\"\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px 0px 12px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"T286Pc\" style=\"margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">95% Conversion &amp; 98% Purity<!--TgQPHd|[]--><\/span>: Our process drives the <span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><a href=\"https:\/\/yohopharm.com\/es\/producto\/epimedium-extract-20-icariin\/\">icariin<\/a><!--TgQPHd|[]--><\/span> conversion rate up to <span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">95%<!--TgQPHd|[]--><\/span> and pushes product purity past <span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">98%<!--TgQPHd|[]--><\/span>, drastically maximizing both yield and quality.<!--TgQPHd|[]--><\/span><!--TgQPHd|[]--><\/li><li class=\"Z1qcYe\" style=\"font-size: 16px; margin: 0px 0px 12px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAIChAG\" data-complete=\"true\" data-sae=\"\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px 0px 12px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"T286Pc\" style=\"margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">Innovative Immobilization Cuts Costs by 70%<!--TgQPHd|[]--><\/span>: By integrating advanced enzyme immobilization technology, the enzyme retains 90% of its initial activity even after 20 repeated uses. This reuse cuts overall enzyme costs by <span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">70%<!--TgQPHd|[]--><\/span>.<!--TgQPHd|[]--><\/span><!--TgQPHd|[]--><\/li><\/ul><\/li><\/ul><p><!--TgQPHd|[]--><\/p><div class=\"n6owBd awi2gc\" style=\"font-family: Arial, sans-serif; font-size: 16px; margin: 12px 0px 16px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAICxAA\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 12px 0px 16px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">Furthermore, our biological approach drastically limits chemical reagent usage, paving the way for eco-friendly, low-pollution manufacturing.<!--TgQPHd|[]--><\/div><div class=\"n6owBd awi2gc\" style=\"font-family: Arial, sans-serif; font-size: 16px; margin: 12px 0px 16px; border-bottom: 0px #0a0a0a;\" data-sfc-cp=\"\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-hveid=\"CAAIDBAA\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 12px 0px 16px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\">Today, our team has officially moved this premium <span class=\"Yjhzub\" style=\"font-weight: 600; margin: 0px; border-bottom: 0px #0a0a0a;\" data-sfc-root=\"c\" data-sfc-cb=\"\" data-complete=\"true\" data-processed=\"true\" data-copy-service-computed-style=\"font-family: Arial, sans-serif; font-size: 16px; font-weight: 600; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"><a href=\"https:\/\/yohopharm.com\/es\/producto\/epimedium-extract-20-icariin\/\">icariin<\/a><!--TgQPHd|[]--><\/span> product into full-scale production. This milestone will accelerate global anti-cancer drug development and ultimately bring life-saving benefits to cancer patients worldwide.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2b2f31d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2b2f31d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8dd1769\" data-id=\"8dd1769\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-746e715 elementor-widget elementor-widget-image\" data-id=\"746e715\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/yohopharm.com\/wp-content\/uploads\/2026\/06\/icariin.jpeg\" class=\"attachment-large size-large wp-image-2389\" alt=\"icariin Enzymatic Epimedium\" srcset=\"https:\/\/yohopharm.com\/wp-content\/uploads\/2026\/06\/icariin.jpeg 500w, https:\/\/yohopharm.com\/wp-content\/uploads\/2026\/06\/icariin-300x300.jpeg 300w, https:\/\/yohopharm.com\/wp-content\/uploads\/2026\/06\/icariin-150x150.jpeg 150w, https:\/\/yohopharm.com\/wp-content\/uploads\/2026\/06\/icariin-12x12.jpeg 12w, https:\/\/yohopharm.com\/wp-content\/uploads\/2026\/06\/icariin-100x100.jpeg 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Icariin, a compound derived from the precious Chinese medicinal herb Epimedium, shows significant therapeutic potential against liver cancer. However, extracting icariin is notoriously difficult. Currently, most market manufacturers rely on chemical extraction or direct synthesis, which yield poor results and cause heavy pollution. While traditional enzymatic methods exist, they use standard commercial enzymes that only [&hellip;]<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[404,403,402],"class_list":["post-2385","post","type-post","status-publish","format-standard","hentry","category-news-center","tag-anticancer","tag-epimedium-extract","tag-icariin"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.7 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Breakthrough: Enzymes Revolutionize Icariin to Boost Cancer Therapy | Shanghai YOH Bio-tech Co., Ltd<\/title>\n<meta name=\"description\" content=\"High-Performance Enzymes Revolutionize Icariin Production to Boost Global Cancer Therapy\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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