Descripción
Introduction of Soybean Phosphatidylcholine
Phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine) is a zwitterionic molecule composed of a hydrophilic head and a hydrophobic tail. It is a type of phospholipid with a choline group inserted at the head. It is an important component of biofilms and can be easily extracted from various sources, such as egg yolks and soybeans, with the usual reagent used for extraction being hexane.
Soybean phosphatidylcholine is also an important component of brown fat in animal and plant tissues. Dipalmitoyl phosphatidylcholine is the main component of alveolar surfactant and is often used in the measurement of L/S ratio (phospholipid/sphingomyelin ratio) to measure the maturity of embryonic lung development. Although all animal and plant cells contain phosphatidylcholine, most bacterial cells, such as Escherichia coli, do not contain phosphatidylcholine.
Phosphatidylcholine is an important component of cell membranes and pulmonary surfactants, more commonly found in the outer lobes of phospholipid bilayers. Phosphatidylcholine transferase is a carrier that transports phosphatidylcholine between membranes. It also plays an important role in cellular signaling pathways.
Specification
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Product Name:
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Phosphatidylcholine Powder
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Spec./Purity:
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20%-50%(Paste), 70%-98%(Powder)
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Appearance:
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Brown Paste(20%-50%) , Light Yellow Powder （70%-98%）
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CAS
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8002-43-5
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MF
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C42H80NO8P
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Effect
- Anti aging
Phosphatidylcholine is a crucial biomolecule that can be found in every cell of the human body. Some scientists have conducted experiments on mice that have undergone genetic mutations leading to oxidative damage and accelerated aging, with the aim of studying whether supplementation with phosphatidylcholine can slow down the aging process, improve brain function, and enhance memory in people older than 70 dementia patients. - Ulcerative colitis
Recent experiments at Heidelberg University Hospital have shown that purified phosphatidylcholine has excellent anti-inflammatory effects and is a surface hydrophobic substance with great prospects in the treatment of ulcerative colitis.
Certificates of Analysis
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Analysis
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Specification
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Result
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Physical Description
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Appearance
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Yellow to brown semi-solid or lump (Internal control)
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Yellow lump
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Solubility
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Soluble in Ether and Ethanol, insoluble in Acetone
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Complies
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Acid value
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30.0 Max
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1.0
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Iodine value
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75.0 Min
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99.4
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Peroxide value
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3.0 Max
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0
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Chemical Tests
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Identification
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(1)
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Should be a positive reaction
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Positive
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(2)
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Should be a positive reaction
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Positive
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Assay(on dry basis)
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Phosphorus (P)
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2.7% Min
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3.8%
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Nitrogen(N)
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1.5%～2.0%
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1.7%
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Phosphatidylcholine
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45.0% Min
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98.31%
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Phosphatidylethanolamine
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30.0% Max
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Not detected
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Phosphatidylcholine and Phosphatidylethanolamine
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70.0% Min
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98.58%
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Protein
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Not detected
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Complies
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Color of solution
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Absorbance 0.8 Max at 350 nm
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0.03
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Acetone insoluble
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90.0% Min
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98.7%
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Hexane insoluble
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0.3% Max
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0.1%
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Water
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1.5% Max
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0.21%
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Residual solvents
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Ethanol 0.2% Max
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0.02%
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Acetone 0.2% Max
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Not detected
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Dichloromethane 0.06% Max
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Not detected
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Total residual solvent 0.5% Max
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0.02%
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Heavy metals
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20.0ppm Max
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Complies
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Pb
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2.0ppm Max
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Complies
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As
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2.0ppm Max
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Complies
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Microbiology Control
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Aerobes [/g] [/g]
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100cfu/g Max
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Complies
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Moulds and Yeasts
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100cfu/g Max
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Complies
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Escherichis coli
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Negative/g
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Not detected
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Salmonellae
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Negative/10g
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Not detected
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Endotoxins
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2.0cfu/g Max
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Complies
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Related substances
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Lysophosphatidyl ethanolamine 1.0% Max
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Not detected
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Lysophosphatidylcholine 3.5% Max
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0.9%
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Lysophosphatidyl ethanolamine and Lysophosphatidylcholine 4.0% Max
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0.9%
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Phosphatidylinositol 5.0% Max
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Not detected
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The total amount of related substances 8.0% Max
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0.9%
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Conclusion
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Complies with China pharmacopoeia 2015 for injection.
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General Status
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Non-GMO, Non-irradiation, ISO.
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Packing and Storage
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Packing: Pack in paper-carton and two plastic-bags inside.
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Shelf life: 2 year when properly stored.
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Storage: Store in a well-closed place with constant low temperature and no direct sun light.
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Valoraciones
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