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• Cardiotonic effect: Hawthorn Extract can increase myocardial contractility, increase cardiac output and slow down heart rhythm.
• Effect on coronary blood flow and myocardial oxygen consumption: hawthorn extract and its total flavonoids can increase coronary blood flow, reduce myocardial oxygen consumption and myocardial oxygen utilization.
• Effect of hawthorn on myocardial nutritional blood flow: Hawthorn has a certain increasing effect on myocardial nutritional blood flow. The increasing effect of hawthorn on myocardial nutritional blood flow may be related to the expansion of coronary artery bed and the improvement of coronary circulation.
• Protective effect on experimental myocardial ischemia: Hawthorn Extract has protective effect on acute myocardial ischemia induced by isoproterenol sulfate in guinea pigs. Hawthorn extract can prevent or reduce myocardial ischemia or necrosis caused by isoproterenol.
• Antihypertensive effect: Hawthorn ethanol extract has a lasting antihypertensive effect.
• Hypolipidemic effect: different extracts of hawthorn have certain lipid-lowering effect on various high-fat models caused by different animals, and can inhibit the increase of serum cholesterol and triglyceride content caused by high-fat diet.