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• Antitumor and immune regulation

Compounds with anticancer activity were isolated from Flammulina velutipes, including polysaccharides from Flammulina velutipes, fungal immune regulatory proteins, steroid compounds, monoterpenes, sesquiterpenes, phenolic acids, glycoproteins, etc. The polysaccharides isolated and purified from Flammulina velutipes have significant anti-tumor activity, mainly inhibiting tumor cell growth through antioxidant and free radical scavenging functions, interfering with tumor cell biochemical metabolism and mitosis, and inducing tumor cell apoptosis to resist tumors.

• Lipid-lowering

The dietary fiber in shiitake mushrooms cannot be broken down by enzymes in the human body and absorbed by the digestive tract. However, it can bind with cholesterol and bile acid, reduce the accumulation of bile acid in the liver, promote cholesterol metabolism to bile acid, reduce cholesterol content in the small intestine, and interfere with the absorption of lipids by the small intestine. The polyphenol compounds extracted from Flammulina velutipes by Rahman et al. also have the effect of delaying LDL oxidation, and have the potential to treat atherosclerosis.

• Antibacterial, anti-inflammatory, and antiviral effects

The polysaccharides from Flammulina velutipes (FVP) not only have anti-tumor and anticancer activities, but also have antibacterial and antifungal activities.

• Improve memory

Polysaccharides from Flammulina velutipes can effectively improve memory impairment caused by scopolamine in rats. The use of polysaccharides from Flammulina velutipes to treat rats can effectively prevent the decrease of antioxidant defense enzyme activity, prevent the increase of thiobarbituric acid reactant content caused by scopolamine, improve brain oxidative stress response, and provide a drug basis for the treatment of brain injury diseases such as Alzheimer’s disease caused by the absence of basal cholinergic neurons in the forebrain, imbalance of reactive oxygen species production and oxidase action in the brain.

In addition, polysaccharides from Flammulina velutipes can maintain levels of neurotransmitters such as dopamine, norepinephrine, and serotonin, which are closely related to learning and memory in the human brain. The use of polysaccharides from Flammulina velutipes to treat memory impairment model mice has been found to effectively improve their learning and memory abilities. Therefore, the golden needle mushroom, also known as the “intelligence mushroom” or “intelligence enhancing mushroom”, has broad prospects for application in brain health and intelligence enhancement. [5]

• Anti-melanin deposition and anti browning

The ergot sulfur found in the golden needle mushroom can significantly reduce the activity of polyphenol oxidase, preventing the melanin deposition or browning of seafood such as shrimp and crabs caused by polyphenol oxidase. The extract of Flammulina velutipes is a natural preparation with excellent anti melanin and anti browning properties, and has great potential for application in the food industry. In addition, the extract of Flammulina velutipes also has application prospects in the whitening cosmetics industry.

• Protecting the liver

In recent years, polysaccharides from Flammulina velutipes have also been found to have liver protective effects. Pang et al. isolated from Flammulina velutipes α (1-4) – D-glucan is a water-soluble polysaccharide FVP2 that can enhance the growth of primary liver cells in mice and inhibit the release of alanine aminotransferase (ALT) in liver cells of mice with acute liver injury caused by carbon tetrachloride. ALT mainly exists in liver cells, and damage or necrosis of liver cells can cause an increase in ALT concentration. ALT is an indicator of the degree of liver cell damage. In addition, polysaccharides from Flammulina velutipes can enhance the activity of liver cell superoxide dismutase.It also can enhance the ability of cells to clear free radicals, reduce the damage of free radicals to cell membranes. Meanwhile，it can inhibit lipid peroxidation reactions, and have the effect of protecting and protecting the liver.

• Anti-skeletal muscle fatigue

Golden needle mushroom polysaccharides have the effect of delaying skeletal muscle fatigue. Sun Hongzhao et al. used electric stimulation of the gastrocnemius muscle in toads as a fatigue model. He found that the solution of polysaccharides from Flammulina velutipes could significantly reduce the contraction amplitude of the gastrocnemius muscle in a dose-dependent manner.

In addition, polysaccharides from Flammulina velutipes can significantly reduce the serum creatine kinase and urea nitrogen content of exercise fatigued rats through immunomodulatory effects. It can increase the activity of lactate dehydrogenase in the blood of rats, accelerate the clearance of lactate in the recovery period of rats after exercise, and promote functional recovery.

The delaying effect of polysaccharides from Flammulina velutipes on skeletal muscle fatigue and the regulatory effect of blood related factors provide a theoretical basis for the study of eliminating exercise fatigue and reducing exercise injuries.

2. Each bag contains 100 servings. add to coffee, tea, smoothies or other foods.

3. Organic Termitomyces eurhizus extract makes from real mushroom fruiting bodies. We actually use the whole real mushroom- not just mycelium grown on grain.

This means it actually contains the beneficial compounds you’re looking for, analytically tested and scientifically verified.

Tested and verified to contain >31% Beta-D glucans

No added fillers, contains <5% starch

USDA Organic Gluten Free, Non-GMO, Vegan and Paleo friendly！